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It also participates in several other important cellular functions such as reactive oxygen species (ROS) generation during mitochondrial respiration, protection against oxidation of membrane lipids, and the redox balance of the cell

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Furthermore, several investigations have indicated that the advantages of acetyl-l-CAR occur without reducing the medicines' anticancer effects (Li et al., 2011, Rebecca et al., 2007)

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Results KAT6A mutations cause a decrease in histone H3 lysine 23 (H3K23) acetylation in human cells and mice To determine the effects of mutation of the KAT6A gene on histone acetylation, we generated human HEK293T cells carrying six different KAT6A variants observed in individuals with ARTHS using CRISPR/Cas9 and homology-directed repair (Tables S1, S2, and S3)

Glutamine and glutamate as vital metabolites