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Patients with advanced prostate cancer are often treated with endocrine therapy including maximal androgen blockade (anti-androgens combined with castration) and classical androgen deprivation (orchiectomy or luteinizing hormone-releasing hormone agonists) [5]

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And yet dehydration remains the root cause of most manageable side effects

Solubility Parameter Approach The functional group contribution method was used to determine the Hansen solubility parameter for the drug and carriers [5]

BayK8644 is a calcium channel agonist and a chemical compound targeting voltage-gated calcium channels and quercetin acts at a site different from Bayk8644 in acting as an insulin secretagogue (Bardy et al., 2013)