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Description
In AD, elevated ROS levels directly promote the oligomerization and aggregation of -amyloid peptides

(2012) 302(11):H22439

Additionally, HDAC6 inhibitors activate redox-regulating proteins like peroxiredoxins (reduce ROS) and support the function of the autophagy and ubiquitin-proteasome system (UPS) (both are impaired in PD patients) 62

Weston, P

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