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In summary, selenium deficiency can impact all aspects of the immune system, while selenium supplementation can improve cellular immunity, humoral immunity, and nonspecific immune functions

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Oxidative folding of interleukin-2 is impaired in flavin-deficient Jurkat cells, causing intracellular accumulation of interleukin-2 and increased expression of stress response genes

doi: 10.1016/j.jff.2015.09.004 191

Similarly, GABA, dopamine, and other neurotransmitters are significantly influenced by gut function