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The IFN- +874 A/A genotype compared to what other genotype can lead to an 8.9 times high risk of OPN, and thus this SNP is a potential susceptibility factor in developing peripheral neuropathy and that cytokine gene polymorphisms do not necessarily exert a major influence on neuropathy but instead probably are contributing factors in increased susceptibility to HIV-SN

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Notartomaso S, Mascio G, Bernabucci M, et al

N., Cho, D., and Li, K

Hyperoxaluria refers to high oxalate concentration in the urine and is seen in 1040% of people with calcium oxalate stones, though it can also be present in individuals without kidney stone disease (Curhan 2012)