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Growth hormone (GH) and epidermal growth factor (EGF) bind to their specific receptors and increase RAS-mediated ERK phosphorylation, which also activates the transcription of genes involved in proliferation and survival
It plays a role in modulating the immune system, reducing inflammation, and supporting overall immune function
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It has been established that tyrosine kinase inhibitors (TKIs) have various cutaneous adverse effects, with skin and hair depigmentation being relatively common but hair repigmentation occurring less frequently 187 - 189
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