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Am J Geriatr Psychiatry 2021;29(5):476477

Older adults, those taking metformin, or those on long-term proton pump inhibitors or H2 blockers with reduced B12 absorption capacity

This structure allows it to resist breakdown in environments that would rapidly destroy other healing peptides

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These structural modifications are designed to enhance peptide stability, resistance to enzymatic degradation, and receptor interaction consistency in laboratory research environments