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Tumor-associated macrophages are shaped by intratumoral high potassium via Kir2.1

4 Benito-KwiecinskiS.LancasterM

Synthetic steroid hormones are used clinically in treating skeletal muscle atrophy, such as testosterone, insulin-like growth factor, and others

doubling the dose does not produce double the response and significantly increases side effect risk (facial flushing, transient tachycardia, headache)

J., Michan S., et al

Under the stimulation of reactive oxygen species (ROS), it releases trans-differentiation inducers to induce the in situ trans-differentiation of Th17 cells into Treg cells for the treatment of MS (Shi et al., 2023)