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An additional in vitro experiment conducted on splenocytes derived from CBA mice showed a substantial effect of Epitalon on the mRNA levels of interleukin-2 (IL-2)

Systemic sclerosis As opposed to RA, in systemic sclerosis, the fibrotic nature of this disease is generally being discussed mainly in the context of pro-fibrotic profile of M2 macrophages [194]

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doi: 10.3390/biomedicines12112540 [DOI] [PMC free article] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article

Anti-Inflammatory Cytokine Reduction: Lowers circulating inflammatory proteins, providing system-wide inflammation control beyond just the local injury site