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Retzius, G

Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse

FDX1 is a small protein from the ferredoxin family and contains an Fe-S cluster ( 2+ and release Cu + into the mitochondrial matrix ( + can directly bind to Fe-S clusters, which in turn disrupt their synthesis and function ( Figure 3 ) ( Figure 3 4 Abnormal copper metabolism and liver disease The liver plays a central role in copper metabolism, including absorption, storage, transportation and excretion

Rosano GL, Ceccarelli EA

Less muscle means a slower metabolism, reduced insulin sensitivity, and shifts in body composition and strength that heighten the risk for weight gain, fatigue, and bone loss over time

Castrn E, Monteggia LM (2021) Brain-derived neurotrophic factor signaling in depression and antidepressant action