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Homocysteine and cardiovascular disease Observational studies indicate that even moderately elevated blood concentrations of homocysteine raise the risk of cardiovascular disease (CVD), although randomized controlled trials of homocysteine-lowering therapy have generally not translated to reductions in adverse cardiovascular outcomes (26, 27)

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Standard doctors such as endocrinologists and family practice providers are conditioned to believe that levothyroxine (the oral version) is the universal treatment for hypothyroidism

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