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Unlike isogenic cohorts 27,29 , the genetic diversity of the DO cohort led to substantial proteomic and metabolomic variations (Extended Data Fig

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10.1038/s41568-023-00650-x 179 RobertF.JeronimoC

difficile infection or other clinically significant intestinal pathogen infection at screening Any identified congenital or acquired immunodeficiency Any live vaccination within 30 days prior to screening or is planning to receive any live vaccination during participation in the study Any of the following laboratory abnormalities during the screening period: Table 1 List of drugs not allowed in the study
