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Moreover, abnormalities in this axis and in cortisol levels can be related to higher cardiovascular risk [164, 165], which may explain the increase in the mortality rate and in the cardiovascular risk factors prevalence observed in affective disorders, including BD [166]

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B12 plays a role in cell reproduction, contributing to the renewal of skin, hair, and nails

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Glutathione's antioxidant action does have a mild protective effect on melanocytes, the cells responsible for hair pigmentation, but it is not formulated or concentrated enough in typical supplement doses to make a meaningful difference to grey hair on its own

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