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p53 has a direct apoptogenic role at the mitochondria
Western Journal of Emergency Medicine , 17 (6), 775782

Lee et al

Treasure Island, FL: StatPearls Publishing (2023)

AOD9604 had a very short half-life of only approximately 3 min after IV injection
Such excipients include various polymers, low molecular weight oligomers, natural products, and surfactants