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Ten of the 12 (83.3%) samples with discrepant subtyping results were sequenced and the results obtained from real-time PCR genotyping were confirmed
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Based on its nucleoside analogue structure, it is tempting to speculate that the drug could impair mitochondrial DNA replication and induce a mitohormetic response ( Taken together, the various effects of rapamycin and adefovir dipivoxil observed here suggest that modulating the expression of both C/EBP- isoforms, LAP and LIP, is likely critical for nutrient homeostasis
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