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Oleocanthal Oleocanthal (Oc), a dialdehydic derivative of decarboxymethyl elenolic acid bound to Tyr, ( p -HPEA-EDA) was shown in vitro to inhibit both COX-1 and COX-2, inflammatory enzymes involved in the biosynthesis of inflammatory prostaglandins in a dose-dependent manner, and to be more effective than ibuprofen in inhibiting these enzymes at equimolar concentrations [260] (see Figure 1)

Pajulas, A., Zhang, J

[...] However, in the last years before its fall, the Hasmonaeans were already strong enough to acquire, partly by negotiation, partly by conquest, a little territory north and south of Judaea and a corridor on the west to the coast at Jaffa/Joppa
Food Research International , 74 , 8088

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Guschina I.A., Harwood J.L
