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EGFR mutant, with IC 50 of 15.6 and 17.0 nM in Del19/T790M/C797S cells and L858R/T790M/C797S cells, respectively [1]

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These findings further underscore the central role of mitochondrial quality control in the multistep evolution of CRC (Fig

The latter study has been performed in human SH-SY5Y neuroblastoma cells