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To our knowledge, vitamin B6 deficiency in association with POEMS syndrome is much rarer than vitamin B12 deficiency in association with POEMS and has only been described in two cases [6]

Furthermore, viral vector-based models demonstrate a similar innate immune response, as seen in toxin-based models

As mentioned previously, NADPH oxidase enzymes are specifically devoted to the production of ROS

Despite these promising works, the exact role of glutathione in AD requires further studies

A residue outside the active site CXXC motif regulates the catalytic efficiency of Glutaredoxin 3

doi: 10.1136/bmj-2022-070750 2 SaundersPTKHorneAW
