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Many clients notice improvements in energy and focus within days, though results vary

[DOI] [PubMed] [Google Scholar] 114.Yukna RA, Krauser JT, Callan DP, Evans GH, Cruz R, Martin M
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Circadian Misalignment Augments Markers of Insulin Resistance and Inflammation, Independently of Sleep Loss

Reviews of the field repeatedly note that the strongest evidence sits in animal and preclinical models , not in large, well-controlled human trials
T.TrottiD.et al (2004)
