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Eur J Neurol 13(12):13241332 Rasmussen MN, Hornbak M, Larsen SS, Sheykhzade M, Edvinsson L (2013) Permanent distal occlusion of middle cerebral artery in rat causes local increased ETB, 5-HT1B and AT1 receptor-mediated contractility downstream of occlusion

Cancer Epidemiol Biomark Prev 10(9):949954 Brown KK, Eriksson SE, Arner ES, Hampton MB (2008) Mitochondrial peroxiredoxin 3 is rapidly oxidized in cells treated with isothiocyanates

Notably, sodium butyrate reduced the expression of NET markers, such as DNA, histones, myeloperoxidase, and neutrophil elastase [49]

in Immunity (2014) Vol.41 pp789-801 CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons Abe, P

The -cyano amide-based Michael acceptors have also been elegantly used by the Taunton group as warheads in small-molecule inhibitors to react with active site cysteines while being minimally affected by the high concentration of intracellular GSH due to the fast reaction kinetics and the mM of K d (refs 31, 32)

Theoretically, oxidative stress can be caused by an increase in the generation of reactive oxygen species, of which mitochondrial dysfunction is believed to be a main source, or it can be caused by a decline in the efficiency of antioxidant enzyme systems