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Glutathione plays a central role as antioxidant defense, as well as in the regulation of pathways involved in cellular homeostasis, not only as a detoxifier of endogenous and exogenous compounds, but also through its participation in processes related to cell proliferation, apoptosis, gene expression, regulation of the immune system, and metabolism of cell compounds, among others

Second, Lys105, Tyr110, Asp144 and Glu147 all stick out on the protein surface, are on top of the scaffold site and form a protein area in a 120 angle to the glutathione-scaffold site (Fig

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doi: 10.1007/s13197-015-1775-6