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Description
A first-in-class, first-in-human, phase I trial of p28, a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in patients with advanced solid tumours

In addition to regulating the activity of the main hepatic enzymes involved in methionine catabolism and regeneration, SAMe stimulates the expression of MAT1A and inhibits the expression of MAT2A and BHMT

CiteSpace II: visualization and knowledge discovery in bibliographic databases

Long-term safety requires explicit attention because several carrier classes show persistent brain retention and immune engagement that can evolve into chronic pathology
corrects hyperpigmentation

Targeted DNA excision in Arabidopsis by a re-engineered homing endonuclease
