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Yes Until 2008 Sermorelin has a unique regulatory history
Regulation of glutamine-repressible gene products by the GLN3 function in Saccharomyces cerevisiae
doi:10.1152/physrev.00003.2005
Mol Cell 49:730742 Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC (2005) Functional interaction between beta-catenin and FOXO in oxidative stress signaling
Regulation of tumor initiation by the mitochondrial pyruvate carrier