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References: Vitamin B 12 CPhA Monograph

Those who opt for the Vitamin B12 injections or IV therapies will experience results faster, within two to three days, due to its quick absorption in the body

The reported adverse reactions following parenteral administration of vitamin B12 include: Generalized: Anaphylaxis and death Cardiovascular: Pulmonary edema and congestive cardiac/heart failure during early treatment

A study in Clinical Therapeutics found that the absorption rate of oral B12 can be significantly lower than that of injections, particularly in older adults or those with digestive disorders

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Also, research shows that B12 absorbs best when dissolved in an isotonic solution like saline