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[27] The connection between GSTP inhibition of the pro-apoptotic JNK pathway and the isozyme's overexpression in drug-resistant tumor cells may itself account for the tumor cells' ability to escape apoptosis mediated by drugs that are not substrates of GSTP
Pathophysiological causation is considered possible by Ishihara et al., but cross-reactivity between Borrelia and other agents suspected to trigger the development of sarcoidosis (molecular mimicry) was not excluded [82]
Academic Press, Oxford, pp 198213
In Stat Pearls: Stat Pearls Publishing (2024)
