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The role of barrier-respecting correction Effective cosmetic correction of a labial melanotic macule requires the same principles as the correction of broader lip hyperpigmentation: gentle exfoliation that respects the barrier, melanin synthesis inhibition at the enzymatic source, and barrier restoration to break the inflammatory cycle

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For example, this occurs in catalase mutants and when catalase activity is inhibited by aminotriazole [90], [91]

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But once you've introduced water, the clock starts ticking

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2025;122:e2413131122

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