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Additionally, pro-inflammatory cytokines such as TNF-, IL-1, and IFN- boost ROS production via mitochondrial and nicotinamide adenine dinucleotide phosphate oxidase pathways [68, 69]

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Those include eating high-quality food and going to the gym

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Melanocytic acral naevi often show quite marked pagetosis, sometimes to the upper levels of the epidermis, which may mimic melanoma in situ

These experiments were repeated twice showing similar results.( To editor : Please replace the "ration" to "ratio" in panel g, We have provided the updated version.) Extended Data Fig