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The dosage is based on medical condition, response to the treatment, age, and weight

Michael Greger, Chief Science Officer at NutritionFacts.org, When selecting a B12 supplement, its important to focus on bioavailability

Clinical Medicine , 15 (2), 145150

Suffice it to say that a 2,000 g/day dose of cyanocobalamin is enough to ensure maximum B12 status in anyone without an extremely rare condition

B12 injections deliver the vitamin directly into muscle, bypassing the digestive system

NICE and BNF Guidance: You correctly point out that even official guidance from NICE and the BNF acknowledges that some individuals may require more frequent injections