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Description
One methyl group

Initially, the mechanisms of action of this enzyme were considered paradoxical because CD38 is predominantly localized on the cell surface, yet its final products are utilized within cytoplasmic compartments

doi: 10.1186/s13045-020-00930-1 64 SunJMuzBAlhallakKMarkovicMGurleySWangZet al

Andres E, Dali-Youcef N, Serraj K et al

In addition to NAD + , CD38 also catabolizes nicotinamide mononucleotide (NMN) and other extracellular NAD + precursors prior to their intracellular transport for NAD + biosynthesis (Fig

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