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However, fresh water reaches its maximum density at a temperature of 4 o C, and as it cools beyond that point its density declines as the hydrogen bonds begin to form and the intermolecular spacing increases (Figure 5.1.5 inset)

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Compounding versions of medications is allowed when it's done by a registered pharmacist in a licensed pharmacy, but even in that case, there's no one independently checking what's being made

BMC Medical Research Methodology 2005;5:13