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By addressing the complex interplay of forces and molecular processes that contribute to ACL injuries, it is possible to improve outcomes for individuals at risk of or recovering from these debilitating injuries (Table 2)

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Research Context Potency: In preclinical studies, Dihexa was shown to be millions of times more potent than BDNF at stimulating synaptogenesis

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Lyophilized peptide is already a stable solid, and -20C storage extends shelf life without damaging the compound

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Plates were incubated at 37C with 5% C0 2 for 48 hours

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Sikiric et al., 2010, 2011, 2012, 2013, 2014, 2016, 2017, 2018) may enable stroke therapy

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