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Increased ROS production has important consequences with respect to signaling by the soluble guanylate cyclase and the cyclic guanosine monophosphate-dependent kinase I, whose activity and expression has been shown to be regulated in a redox-sensitive manner
2.8.1 Basic science research Nigral iron deposition is demonstrated in in-vivo rat models of PD (Xiu et al., 2025)

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Targeting mitochondrial quality control: new therapeutic strategies for major diseases
