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Very high values IGF-1 were associated with a better prognosis of ALS suggesting that functions related to IGF-1 could be involved in survival
10.1023/B:ANTO.0000020152.15440.65

Barnett, F

However, inhibition of GLS activity can reduce ATP and GSH levels produced by cardiomyocytes under oxidative stress conditions

10.1677/joe.0.1250271

The therapeutic strategy mentioned in the text involves targeting immune organs to counteract immunosenescence by restoring thymic vitality, rejuvenating bone marrow niches, and improving the function of peripheral immune organs, ultimately enhancing the generation and functionality of immune cells
