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Finally, a 2017 Cochrane systematic review and meta-analysis of 20 randomized controlled trials reported a small benefit of omega-3 supplementation on depressive symptoms when compared to placebo, yet the evidence was deemed of very low quality and the positive effect was judged likely to be biased and not clinically significant (195)

J Cell Biochem 82, 387398 (2001)

Because they contain phosphoric acid, they are also classified as phospholipids

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