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These alterations result from generation of highly reactive free radicals leading to peroxidation of membrane phospolypids rich in polyunsaturated fatty acids, particularly in conditions with increased intracellular iron and decreased antioxidant systems (namely glutathione) (Hirschhorn and Stockwell, 2019)

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Research on these therapies points to a positive impact of senescence induction, particularly in the initial stages of the disease [8]

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The response of CD24 (/low) /CD44 + breast cancer-initiating cells to radiation