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We next asked if a mitochondrial route might be involved since both glucose and fatty acids can feed mitochondrial acetyl-CoA pools (Figure 5A

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[14] [15] [16] [17] There are three redox states of CoQ: fully oxidized ( ubi quinone), semi quinone ( ubisemi quinone), and fully reduced (ubiquinol)

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4) Clinical Carnitine Deficiency Syndrome Two distinct carnitine deficiency states have been reported, which include "primary" and "secondary" carnitine deficiency

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doi: 10.1186/s40168-021-01046-5 47 ChynowethJHoskingJJefferyAPinkneyJ

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