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When -glutamyl-p-nitroanilide is used as the substrate for hydrolysis, the formation step of the acyl enzyme is faster than the step for the water-conducted breakdown of the intermediate, as shown by the faster reaction rate for the transpeptidation reaction compared with that of hydrolysis [86]

10.3345/kjp.2017.60.4.106 Korean J Pediatr

Many dissociatives have general depressant effects and can produce sedation, respiratory depression, analgesia, anesthesia, and ataxia, as well as cognitive and memory impairment and amnesia