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(2008) High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial

Clinical trials demonstrate a clear dose-response relationship, with higher doses producing greater HbA1c reductions and weight loss

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In each group, 6 mice were randomly selected after 3 and 7 days of the administration to detect the amount of tear secretion and corneal FLS staining in both eyes (n = 12), and 3 mice were randomly selected to extract eye tissue for lacrimal and corneal HE staining and TUNEL staining

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Aging decreases mitochondrial electron transport at complex III
