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The Four Enemies of Peptide Stability 1

van Vollenhoven RF, Bertsias G, Doria A et al (2021) DORIS definition of remission in SLE: final recommendations from an international task force

As a by-product of respiration, the mitochondria produce superoxide, which may be dismutated to hydrogen peroxide that activates these channels, thereby regulating the voltage-dependent influx of calcium and the activity of caspases

This reflects a key implication in malignancies, whose intrinsic environment is highly dependent on glycolysis, as characterized by the Warburg effect

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