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This usually starts with a very thorough health history, listening carefully to your story and symptoms

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We have used this approach to predict treatment outcomes and to identify specific metabolomic pathways that were changed in response to sertraline 34,35 and to ketamine 36 , a promising agent for treatment-resistant depression

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After IM injection, the onset of analgesia occurs in about 30 minutes, with a peak effect around 1 to 2 hours, and a duration of action of 4 to 6 hours