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ChenNYXieYLLuGDYeFLiXYHuangYWet alSynthesis and antitumor evaluation of (Aryl)methyl-amine derivatives of dehydroabietic acid-based B ring-fused-thiazole as potential Pi3k/Akt/Mtor signaling pathway inhibitors

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This dual action, reducing inflammation while simultaneously calming overactive pain pathways, may explain why ARA-290 shows effectiveness where other approaches fail