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We noted that the lung to body weight ratio was indeed elevated in AA-exposed mice compared to PBS and melatonin-only controls, however the extent of this increase was substantially reduced in those mice which received melatonin alongside AA ( Figure 1B )

This multifaceted immunomodulation shifts the immune balance from pro-inflammatory to anti-inflammatory states, thereby reducing neuroinflammation and preserving neuronal integrity in PD pathogenesis

In summary, the treatment of PD has entered an era of integrated management characterized by the synergy between pharmacological and non-pharmacological approaches, equal emphasis on symptomatic and causative treatment, and consideration of both present and future needs

Promotes healthy oxygen circulation for better vitality
For a 16-week protocol , total projected use is about 78.4 mg , so 8 vials would usually be needed
