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Conceivably, endogenous CoQ levels and the contributions of CoQ to ROS production and cellular antioxidant status differ in different cell types and under different conditions
A.MarschR.DragoF.et al (2017)

HIV-1 with multiple TAMs (M41L, D67N, K70R, L210W, T215F/Y, K219Q/E/N/R), or multinucleoside resistant HIV-1 with a T69S double insertion mutation or with a Q151M mutation complex including K65R, showed reduced susceptibility to TAF in cell culture

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