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Recent studies support the notion that diets rich in micronutrients that play a role in the one-carbon metabolism have promising effects in mitigating AD pathogenesis [67,135,136,137,138,139]

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These models offer several advantages, such as the preservation of complex architectural structures, ease of handling and analysis, and relevant biological properties (Figure 8)

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Biochem Biophys Res Commun 372 , 367372, (2008)

Pediatric patients are at higher risk for cold injury due to their smaller ratio of body mass to body surface area
