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Although routine B12 supplementation in patients on metformin therapy is not the standard of care (279), it is reasonable to monitor vitamin B12 levels in patients on metformin, particularly for individuals on long-term metformin (102

doi: 10.1016/B978-0-12-394440-5.00002-4

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Am J Kidney Dis 2012

Similar results were achieved by Schauer and colleagues, in a model of warm ischemia, followed by isolated rat liver perfusion [221]
