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Following that, RIPK1 interacts with RIPK3 via their RIP homotypic interaction motifs (RHIMs), driving the assembly of the high-molecular-weight amyloid-like necrosome (16)

Determination of hepatic TG Levels Hepatic TG accumulation was determined by both histochemical detection (Oil Red O staining) and biochemical assays

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130 SanderC.VoelterH.-U.SchlakeH.-P.ElingP.HildebrandtH

For example, T cell activation upregulates a variety of amino acid transporters, including SLC7A5, and deletion of SLC7A5 leads to activation of the mTOR signaling pathway and upregulation of the transcription factor MYC to inhibit T cell proliferation

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