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This observation is in line with other experimental studies showing similar pronounced GR- downregulation in the hippocampus and other regulatory centres of the HPA axis [33]

rosea containing 3% rosavin and 1% salidroside on CNS activity in mice
Kalaany and Sabatini had shown in NOD-SCID (non-obese diabetic, severe combined immunodeficient) mice that xenografted tumors with constitutive activation of AKT by either gains in PIK3CA or loss of PTEN are resistant against CR, and insensitive to insulin and IGF-1 treatment in vitro
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Gach, J