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For more severe sprains where ligaments holding the joint together are torn, surgery may be needed to restore stability to the joint

GSH protects endothelial cells by neutralizing ROS and sustaining NO levels

Additionally, hyperglycemia has been observed to promote oxidative stress through the generation of free radicals and the suppression of antioxidant defense systems [16]

Anti-type II collagen immune complex-induced granulocyte reactivity is associated with joint erosions in RA patients with anti-collagen antibodies

Guinea pigs (Hartley, both sexes, 500-700 g b.w.) with whole body plethysmography, urethane anesthesia (1.5 g/kg i.p.), artificial ventilation under constant pressure (0.98 kPa), and relaxation of skeleton musculature by suxamethonium (0.2 mg/kg i.v.) were used in the present experiments