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Increasing evidence supports lactate-mediated lactylation as a critical modulator in neurological disorders
Additionally, neurofibrillary tangles formed by hyperphosphorylated tau proteins reduce their binding affinity with neuronal tubulin, destabilizing microtubules and promoting neurodegeneration (Savastano et al., 2021
Growth Factor and Exosome Therapies Investigational approaches using fibroblast growth factor-2 and neurotrophic factors to enhance nerve repair and vascularization [144]
Morbidity and mortality in 928 Doberman Pinschers born in the Netherlands between 1993 and 1999
The pathway is quite efficient: for example, it maintains the ratio NADPH/NADP+ at ~100 in the liver of a normal healthy individual
Cell Signal 26 (3), 512520
