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doi:10.1016/S2666-7568(22)00096-4 Sood A, Hosseinpour A, Sood A, et al

Studies have found that inhibiting KGDD activity due to mutations in IDH1/2, FH, or SDH increases sensitivity to DNA damaging agents, and the mechanisms described are due to changes in methylation (Inoue et al., 2016

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Electron microscopy analysis confirmed this AP reduction (Supplementary Fig

Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, et al
